Microbiology techniquesProtein stubs biochemistrymacromoleculepHvoltagelightchromophoresionphosphorylationligandcrystallographyNMRelectron paramagnetic resonancespin labelcircular dichroism (CD)hydrogen exchangeFRETDual polarisation interferometryelectro-switchable biosurfaces Main article: Protein dynamics In biochemistry, a conformational change is a change in the shape of a macromolecule, often induced by environmental factors. A macromolecule is usually flexible and dynamic. It can change its shape in response to changes in its environment or other factors; each possible shape is called a conformation, and a transition between them is called a conformational change . Factors that may induce such changes include temperature, pH, voltage, light in chromophores, ion concentration, phosphorylation, or the binding of a ligand. Contents 1 Laboratory analysis 2 See also 3 External links 4 References Laboratory analysis Many biophysical techniques such as crystallography, NMR, electr...