Imidafenacin References Navigation menu170105-16-564330904938278XJR8Y07LJOChEMBL53366100.216.585Interactive image(verify)10.1055/s-0031-129658917396619"Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents"10.1016/S0968-0896(99)00003-610428387eeexpanding ite

Ammonium chlorideCalcium chlorideUreaAcetohydroxamic acidSalicylhydroxamic acidCollagenDimethyl sulfoxideMagnesium hydroxidePentosan polysulfatePhenazopyridinePhenyl salicylateSuccinimide77-LH-28-1AC-42AC-260,584AceclidineAcetylcholineAF30AF150(S)AF267BAlvamelineAQRA-741ArecolineBethanecholBevoniumButyrylcholineCarbacholCDD-0034CDD-0078CDD-0097CDD-0098CDD-0102CevimelineCholinecis-DioxolaneClozapineDesmethylclozapine (norclozapine)EthoxysebacylcholineItamelineLY-593,039L-689,660LY-2,033,298McNA343MethacholineMilamelineMuscarineNGX-267OcvimelineOxotremorinePD-151,832PilocarpineRS86SabcomelineSDZ 210-086SebacylcholineSuberyldicholineTalsaclidineTazomelineThiopilocarpineVedaclidineVU-0029767VU-0090157VU-0152099VU-0152100VU-0238429WAY-132,983XanomelineYM-7963-Quinuclidinyl benzilate4-DAMPAclidinium bromide+formoterolAbediterolAF-DX 250AF-DX 384Ambutonium bromideAnisodamineAnisodineAntihistamines (first-generation)brompheniraminebuclizinecaptodiamechlorphenamine (chlorpheniramine)cinnarizineclemastinecyproheptadinedimenhydrinatedimetindenediphenhydraminedoxylaminemeclizinemepyramine (pyrilamine)mequitazineperlapinephenindaminepheniraminephenyltoloxaminepromethazinepropiomazinetriprolidineAQ-RA 741AtropineAtropine methonitrateAtypical antipsychoticsclozapinefluperlapineolanzapine+fluoxetinerilapinequetiapinetenilapinezotepineBenactyzineBenzatropine (benztropine)BenziloneBenzilylcholine mustardBenzydamineBIBN 99BiperidenBornaprineCamylofinCAR-226,086CAR-301,060CAR-302,196CAR-302,282CAR-302,368CAR-302,537CAR-302,668CaramiphenCimetropium bromideClidinium bromideCloperastineCS-27349CyclobenzaprineCyclopentolateDarifenacinDAU-5884DesfesoterodineDexetimideDIBDDicycloverine (dicyclomine)DihexyverineDifemerineDiphemanil metilsulfateDitranEA-3167EA-3443EA-3580EA-3834Emepronium bromideEtanautineEtybenzatropine (ethybenztropine)FenpiveriniumFentonium bromideFesoterodineFlavoxateGlycopyrronium bromide+beclometasone/formoterol+indacaterolHexahydrodifenidolHexahydrosiladifenidolHexbutinolHexocycliumHimbacineHL-031,120HomatropineImidafenacinIpratropium bromide+salbutamolIsopropamideJ-104,129HyoscyamineMamba toxin 3Mamba toxin 7MazaticolMebeverineMeladrazineMepenzolateMethanthelineMethoctramineMethylatropineMethylhomatropineMethylscopolamineMetixeneMuscarinic toxin 7N-Ethyl-3-piperidyl benzilateN-Methyl-3-piperidyl benzilateNefopamOctatropine methylbromide (anisotropine methylbromide)OrphenadrineOtenzepad (AF-DX 116)Otilonium bromideOxapium iodideOxitropium bromideOxybutyninOxyphencyclimineOxyphenonium bromidePBIDPD-102,807PD-0298029PenthienatePethidinepFHHSiDPhenglutarimidePhenyltoloxaminePipenzolate bromidePiperidolatePirenzepinePiroheptinePizotifenPoldinePridinolPrifinium bromideProcyclidineProfenamine (ethopropazine)Propantheline bromidePropiverineQuinidineRevefenacinRociverineRU-47,213SCH-57,790SCH-72,788SCH-217,443Scopolamine (hyoscine)Scopolamine butylbromide (hyoscine butylbromide)SilahexacycliumSofpironium bromideSolifenacinSSRIsfemoxetineparoxetineTelenzepineTerodilineTetracyclic antidepressantsamoxapinemaprotilinemianserinmirtazapineTiemonium iodideTimepidium bromideTiotropium bromideTiquizium bromideTofenacinTolterodineTricyclic antidepressantsamitriptyline+perphenazineamitriptylinoxidebutriptylinecidoxepinclomipraminedesipraminedesmethyldesipraminedibenzepindosulepin (dothiepin)doxepinimipraminelofepraminenitroxazepinenorthiaden (desmethyldosulepin)nortriptylineprotriptylinequinupraminetrimipramineTridihexethylTrihexyphenidylTrimebutineTripitamine (tripitramine)TropacineTropatepineTropicamideTrospium chlorideTypical antipsychoticschlorpromazinechlorprothixenecyamemazine (cyamepromazine)loxapinemesoridazinethioridazineUmeclidinium bromide+vilanterolWIN-2299XanomelineZamifenacinAcetyl-coAAdafenoxateCholinelecithinCiticolineCyprodenateDimethylethanolamineGlycerophosphocholineMeclofenoxate (centrophenoxine)PhosphatidylcholinePhosphatidylethanolaminePhosphorylcholinePirisudanol


Drugs not assigned an ATC codeMuscarinic antagonistsImidazolesCarboxamidesGenito-urinary system drug stubs


INNurinaryantispasmodicanticholinergic





























Imidafenacin
Imidafenacin.png
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status

  • In general: ℞ (Prescription only)

Identifiers
CAS Number

  • 170105-16-5 ☑Y

PubChem CID
  • 6433090
ChemSpider

  • 4938278 ☒N
UNII
  • XJR8Y07LJO
ChEMBL

  • ChEMBL53366 ☒N
ECHA InfoCard
100.216.585 Edit this at Wikidata
Chemical and physical data
Formula
C20H21N3O
Molar mass319.40 g/mol g·mol−1
3D model (JSmol)
  • Interactive image

.mw-parser-output .noboldfont-weight:normal
 ☒N☑Y (what is this?)
  (verify)

Imidafenacin (INN) is a urinary antispasmodic of the anticholinergic class. Its molecular weight is 319.40 g/mol



References



  • Kobayashi F, Yageta Y, Segawa M, Matsuzawa S (2007). "Effects of imidafenacin (KRP-197/ONO-8025), a new anti-cholinergic agent, on muscarinic acetylcholine receptors. High affinities for M3 and M1 receptor subtypes and selectivity for urinary bladder over salivary gland". Arzneimittelforschung. 57 (2): 92–100. doi:10.1055/s-0031-1296589. PMID 17396619..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em


  • Miyachi H, Kiyota H, Uchiki H, Segawa M (June 1999). "Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents". Bioorg. Med. Chem. 7 (6): 1151–61. doi:10.1016/S0968-0896(99)00003-6. PMID 10428387.








Carboxamides, Drugs not assigned an ATC code, Genito-urinary system drug stubs, Imidazoles, Muscarinic antagonistsUncategorized
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