Imidafenacin References Navigation menu170105-16-564330904938278XJR8Y07LJOChEMBL53366100.216.585Interactive image(verify)10.1055/s-0031-129658917396619"Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents"10.1016/S0968-0896(99)00003-610428387eeexpanding ite

Ammonium chlorideCalcium chlorideUreaAcetohydroxamic acidSalicylhydroxamic acidCollagenDimethyl sulfoxideMagnesium hydroxidePentosan polysulfatePhenazopyridinePhenyl salicylateSuccinimide77-LH-28-1AC-42AC-260,584AceclidineAcetylcholineAF30AF150(S)AF267BAlvamelineAQRA-741ArecolineBethanecholBevoniumButyrylcholineCarbacholCDD-0034CDD-0078CDD-0097CDD-0098CDD-0102CevimelineCholinecis-DioxolaneClozapineDesmethylclozapine (norclozapine)EthoxysebacylcholineItamelineLY-593,039L-689,660LY-2,033,298McNA343MethacholineMilamelineMuscarineNGX-267OcvimelineOxotremorinePD-151,832PilocarpineRS86SabcomelineSDZ 210-086SebacylcholineSuberyldicholineTalsaclidineTazomelineThiopilocarpineVedaclidineVU-0029767VU-0090157VU-0152099VU-0152100VU-0238429WAY-132,983XanomelineYM-7963-Quinuclidinyl benzilate4-DAMPAclidinium bromide+formoterolAbediterolAF-DX 250AF-DX 384Ambutonium bromideAnisodamineAnisodineAntihistamines (first-generation)brompheniraminebuclizinecaptodiamechlorphenamine (chlorpheniramine)cinnarizineclemastinecyproheptadinedimenhydrinatedimetindenediphenhydraminedoxylaminemeclizinemepyramine (pyrilamine)mequitazineperlapinephenindaminepheniraminephenyltoloxaminepromethazinepropiomazinetriprolidineAQ-RA 741AtropineAtropine methonitrateAtypical antipsychoticsclozapinefluperlapineolanzapine+fluoxetinerilapinequetiapinetenilapinezotepineBenactyzineBenzatropine (benztropine)BenziloneBenzilylcholine mustardBenzydamineBIBN 99BiperidenBornaprineCamylofinCAR-226,086CAR-301,060CAR-302,196CAR-302,282CAR-302,368CAR-302,537CAR-302,668CaramiphenCimetropium bromideClidinium bromideCloperastineCS-27349CyclobenzaprineCyclopentolateDarifenacinDAU-5884DesfesoterodineDexetimideDIBDDicycloverine (dicyclomine)DihexyverineDifemerineDiphemanil metilsulfateDitranEA-3167EA-3443EA-3580EA-3834Emepronium bromideEtanautineEtybenzatropine (ethybenztropine)FenpiveriniumFentonium bromideFesoterodineFlavoxateGlycopyrronium bromide+beclometasone/formoterol+indacaterolHexahydrodifenidolHexahydrosiladifenidolHexbutinolHexocycliumHimbacineHL-031,120HomatropineImidafenacinIpratropium bromide+salbutamolIsopropamideJ-104,129HyoscyamineMamba toxin 3Mamba toxin 7MazaticolMebeverineMeladrazineMepenzolateMethanthelineMethoctramineMethylatropineMethylhomatropineMethylscopolamineMetixeneMuscarinic toxin 7N-Ethyl-3-piperidyl benzilateN-Methyl-3-piperidyl benzilateNefopamOctatropine methylbromide (anisotropine methylbromide)OrphenadrineOtenzepad (AF-DX 116)Otilonium bromideOxapium iodideOxitropium bromideOxybutyninOxyphencyclimineOxyphenonium bromidePBIDPD-102,807PD-0298029PenthienatePethidinepFHHSiDPhenglutarimidePhenyltoloxaminePipenzolate bromidePiperidolatePirenzepinePiroheptinePizotifenPoldinePridinolPrifinium bromideProcyclidineProfenamine (ethopropazine)Propantheline bromidePropiverineQuinidineRevefenacinRociverineRU-47,213SCH-57,790SCH-72,788SCH-217,443Scopolamine (hyoscine)Scopolamine butylbromide (hyoscine butylbromide)SilahexacycliumSofpironium bromideSolifenacinSSRIsfemoxetineparoxetineTelenzepineTerodilineTetracyclic antidepressantsamoxapinemaprotilinemianserinmirtazapineTiemonium iodideTimepidium bromideTiotropium bromideTiquizium bromideTofenacinTolterodineTricyclic antidepressantsamitriptyline+perphenazineamitriptylinoxidebutriptylinecidoxepinclomipraminedesipraminedesmethyldesipraminedibenzepindosulepin (dothiepin)doxepinimipraminelofepraminenitroxazepinenorthiaden (desmethyldosulepin)nortriptylineprotriptylinequinupraminetrimipramineTridihexethylTrihexyphenidylTrimebutineTripitamine (tripitramine)TropacineTropatepineTropicamideTrospium chlorideTypical antipsychoticschlorpromazinechlorprothixenecyamemazine (cyamepromazine)loxapinemesoridazinethioridazineUmeclidinium bromide+vilanterolWIN-2299XanomelineZamifenacinAcetyl-coAAdafenoxateCholinelecithinCiticolineCyprodenateDimethylethanolamineGlycerophosphocholineMeclofenoxate (centrophenoxine)PhosphatidylcholinePhosphatidylethanolaminePhosphorylcholinePirisudanol


Drugs not assigned an ATC codeMuscarinic antagonistsImidazolesCarboxamidesGenito-urinary system drug stubs


INNurinaryantispasmodicanticholinergic





























Imidafenacin
Imidafenacin.png
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status

  • In general: ℞ (Prescription only)

Identifiers
CAS Number

  • 170105-16-5 ☑Y

PubChem CID
  • 6433090
ChemSpider

  • 4938278 ☒N
UNII
  • XJR8Y07LJO
ChEMBL

  • ChEMBL53366 ☒N
ECHA InfoCard
100.216.585 Edit this at Wikidata
Chemical and physical data
Formula
C20H21N3O
Molar mass319.40 g/mol g·mol−1
3D model (JSmol)
  • Interactive image

.mw-parser-output .noboldfont-weight:normal
 ☒N☑Y (what is this?)
  (verify)

Imidafenacin (INN) is a urinary antispasmodic of the anticholinergic class. Its molecular weight is 319.40 g/mol



References



  • Kobayashi F, Yageta Y, Segawa M, Matsuzawa S (2007). "Effects of imidafenacin (KRP-197/ONO-8025), a new anti-cholinergic agent, on muscarinic acetylcholine receptors. High affinities for M3 and M1 receptor subtypes and selectivity for urinary bladder over salivary gland". Arzneimittelforschung. 57 (2): 92–100. doi:10.1055/s-0031-1296589. PMID 17396619..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em


  • Miyachi H, Kiyota H, Uchiki H, Segawa M (June 1999). "Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents". Bioorg. Med. Chem. 7 (6): 1151–61. doi:10.1016/S0968-0896(99)00003-6. PMID 10428387.








Carboxamides, Drugs not assigned an ATC code, Genito-urinary system drug stubs, Imidazoles, Muscarinic antagonistsUncategorized
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Nikolai Prilezhaev Bibliography References External links Navigation menuEarly Russian Organic Chemists and Their Legacy092774english translationRussian Biography

19th-century chemists20th-century chemists1877 births1944 deathsRussian chemists RussianO.S.KopossevoNizhny NovgorodMoscoworganic chemistPrilezhaev ReactionepoxidesalkenesperoxyacidsUniversity of WarsawYegor Yegorovich VagnerGeorg WagnerSt. PetersburgPolytechnic in KievUniversity of MinskBelarusian Academy of SciencesAlexei Nikolaevich Bachname reactionSoviet Academy of Sciences Nikolai Alexandrovich Prilezhaev , Russian: Николай Александрович Прилежаев , (Born 15 [O.S. 1877] 27 [1] in Kopossevo near Nizhny Novgorod, died May 26, 1944 in Moscow) was a Russian organic chemist. The Prilezhaev Reaction between epoxides and alkenes to form peroxyacids is named after him. Prilezhaev was the son of a clergyman and studied chemistry at the Theological Seminary in Warsaw (graduated in 1895) and then at the Univ...
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